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“I had my gall bladder out on 12/14, and have had no problems with alcohol (unless I consumed too much, in which case I knew what I was in for).

As others have said, it all depends on the individual’s body. Tread lightly, and if you’re not feeling great the next day – drink plenty of water, have some juice, rest if you can, and if you have “”spinning”” then I’ve heard Benadryl can help that (it’s broken down by your body into the same effective component of motion sickness pills).”