Author: Finlay A Macrae, MD Section Editors: Richard M Goldberg, MD David Seres, MD Deputy Editor: Diane MF Savarese, MD SUMMARY for Cholecystectomy Cholecystectomy — A relationship between cholecystectomy and right-sided colon cancer has been described in some reports. As an example, in a study of 278,460 patients followed for up to 33 years after surgery, patients who […]

Cholecystectomy and colorectal cancer Ekbom, Anders et al. Gastroenterology , Volume 105 , Issue 1 , 142 – 147 https://www.gastrojournal.org/article/0016-5085(93)90019-9/abstract Abstract : An increased risk of large bowel cancer, especially of the right colon, following cholecystectomy has been reported in some studies but contradicted in others. The aim of this study was to settle this question […]

  Leticia Nogueira Neal D. Freedman Eric A. Engels Joan L. Warren Felipe CastroJill Koshiol American Journal of Epidemiology, Volume 179, Issue 6, 15 March 2014, Pages 731–739,https://doi.org/10.1093/aje/kwt322 Published: 26 January 2014 Article history   Abstract Gallstones and cholecystectomy may be related to digestive system cancer through inflammation, altered bile flux, and changes in metabolic hormone levels. Although gallstones […]

Syeda NS Gilani, Royal College of Surgeons in Ireland Date of Award 2012 Document type, Thesis Gastric Mucosa, Cholecystectomy Abstract Chronic exposure of oesophageal mucosa to bile has been implicated in the etiology of the oesophageal lesions which develop into Barrett’s oesophagus.Loss of the gallbladder reservoir function at cholecystectomy may critically alter the dynamics of bile […]

Yong Zhang , Hao Liu , Li Li , Min Ai , Zheng Gong, Yong He, Yunlong Dong, Shuanglan Xu, Jun Wang , Bo Jin, Jianping Liu, Zhaowei Teng Published: August 3, 2017https://doi.org/10.1371/journal.pone.0181852   Abstract Objective This study aimed to elucidate the effects of cholecystectomy on the risk of colorectal cancer (CRC) by conducting a […]

Leticia Nogueira*, Neal D. Freedman, Eric A. Engels, Joan L. Warren, Felipe Castro, and Jill Koshiol * Correspondence to Dr. Leticia Nogueira, National Cancer Institute, 9609 Medical Center Drive, MSC 7248, Bethesda, MD 20892 (e-mail: leticia.nogueira@nih.gov). Initially submitted July 3, 2013; accepted for publication November 26, 2013. Gallstones and cholecystectomy may be related to digestive […]

The gallbladder is a small pear shaped organ located near the lower border of liver. The bile which is secreted by the liver and which is essential for the digestion of fat in the small intestine is stored in the gallbladder. Gallbladder — A Small Pear Shaped Organ Gallbladder disease includes stone formation and infection. In many […]

  More than 60 epidemiologic studies have investigated a possible relation between cholecystectomy and colon cancer risk. However, the strength of any association remains uncertain because of the small size and retrospective design with a failure to control for potential confounders of most analyses. A meta-analysis of studies conducted through 1993 (Giovannucci et al, 1993) observed […]