Postcholecystectomy - Cancer Risk

Colorectal cancer: Epidemiology, risk factors, and protective factors

Author: Finlay A Macrae, MD Section Editors: Richard M Goldberg, MD David Seres, MD Deputy Editor: Diane MF Savarese, MD SUMMARY for Cholecystectomy Cholecystectomy — A relationship between cholecystectomy and right-sided colon cancer has been described in some reports. As an example, in a study of 278,460 patients followed for up to 33 years after surgery, patients who […]

Cholecystectomy and colorectal cancer

Cholecystectomy and colorectal cancer Ekbom, Anders et al. Gastroenterology , Volume 105 , Issue 1 , 142 – 147 Abstract : An increased risk of large bowel cancer, especially of the right colon, following cholecystectomy has been reported in some studies but contradicted in others. The aim of this study was to settle this question […]

Gallstones, Cholecystectomy, and Risk of Digestive System Cancers

  Leticia Nogueira Neal D. Freedman Eric A. Engels Joan L. Warren Felipe CastroJill Koshiol American Journal of Epidemiology, Volume 179, Issue 6, 15 March 2014, Pages 731–739, Published: 26 January 2014 Article history   Abstract Gallstones and cholecystectomy may be related to digestive system cancer through inflammation, altered bile flux, and changes in metabolic hormone levels. Although gallstones […]

Effects of cholecystectomy on gastric and oesophageal mucosa.

Syeda NS Gilani, Royal College of Surgeons in Ireland Date of Award 2012 Document type, Thesis Gastric Mucosa, Cholecystectomy Abstract Chronic exposure of oesophageal mucosa to bile has been implicated in the etiology of the oesophageal lesions which develop into Barrett’s oesophagus.Loss of the gallbladder reservoir function at cholecystectomy may critically alter the dynamics of bile […]

Gallstones, Cholecystectomy, and Risk of Digestive System Cancers

Leticia Nogueira*, Neal D. Freedman, Eric A. Engels, Joan L. Warren, Felipe Castro, and Jill Koshiol * Correspondence to Dr. Leticia Nogueira, National Cancer Institute, 9609 Medical Center Drive, MSC 7248, Bethesda, MD 20892 (e-mail: Initially submitted July 3, 2013; accepted for publication November 26, 2013. Gallstones and cholecystectomy may be related to digestive […]

Reasons To Avoid Getting Gallbladder Removed

The gallbladder is a small pear shaped organ located near the lower border of liver. The bile which is secreted by the liver and which is essential for the digestion of fat in the small intestine is stored in the gallbladder. Gallbladder — A Small Pear Shaped Organ Gallbladder disease includes stone formation and infection. In many […]

Cholecystectomy and the risk for developing colorectal cancer and distal colorectal adenomas

  More than 60 epidemiologic studies have investigated a possible relation between cholecystectomy and colon cancer risk. However, the strength of any association remains uncertain because of the small size and retrospective design with a failure to control for potential confounders of most analyses. A meta-analysis of studies conducted through 1993 (Giovannucci et al, 1993) observed […]